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PROFESSIONAL, SCIENCE, ATTENTION

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Lactibacillus rhamnosus TCELL-1

Property:

  • "TCELL-1 POWDER" had got Taiwan Health Supplement Food Authorization No. A00042th.
  • Had ¡§Certificate of the First International Biotechnology and Medical Care Innovatious Award¡¨ and ¡§Certificate of Nominee for 2002 National Biotechnology and Medical Care Award¡¨.
  • Human source: TCELL-1 was isolated from human gut.
  • Had applied for ten countries patents, had attained Mainland of China and Singapore letter patent.
  • TCELL-1 has been full sequencing on 16s rDNA.

Research projects and achievements:

  • National Tsing Hua University¡GThe mucous membrane immunity of intestinal tract (animal experiment):
  • Increase the immune body IgA, IgM secretion quantity.
  • Integrity DNA secquencing (in vitro): Approximately 863bp 16S
  • rDNA had been secquencing.
  • The anti- gastric juice, bile salt (in vitro and the animal experiment): Still survive at pH 2.5 for 4 hours, 1% bile salt for 4 hours.
  • The adherence to intestinal tract experiment (animal experiment): May adhere to the intestinal tract.
  • Suppresses the harmful bacteria experiment (in vitro): May suppress 14
  • kind of harmful bacteria.
  • Note: The following harmful bacteria are everlasting discovered in each kind of dairy milk products.
  1. Vibrio furnissii 
  2. Vibrio vulnificus  
  3. Shigella flexneri  
  4. Shigella dysenteriae 
  5. Staphylococcus aureus 
  6. Enterococcus faecalis
  7. Bacillus cereus  
  1. Listeria monocytogenes  
  2. Streptococcus mutans
  3. Yersinia enterocolitica 
  4. Citrobacter freundii 
  5. Serratia entomophila  
  6. Clostridium perfringens
  7. Klebsiella pneumoniae subsp Peumoniae
  • The adherence on human intestinal tract experiment: May adhere on the human intestines and reaches 2 weeks above the time.
  • TCELL-1 and isomalt regarding SD rat's intestinal tract bacteria influence (animal experiment): May increase in vivo to benefit the fresh bacteria colony (Lactobacillus, Bifidobacterium), May adjust in the intestinal ecology batter condition.
  • Food Industry Research and Development Institute : Lactobacillus stability experiment: May deposit above for a year at 4 ¢J .
  • Intestinal function improvement appraisal (animal experiment): May increase in vivo to benefit bacterial colony (Lactobacillus, Bifidobacterium), may adjust in the intestinal bacterial ecology condition.
  • Immunity adjustment effect (animal experiment): Increase natural killer cell activity and lymphocyte IL-2.
  • Laboratory Animal Center , National Taiwan University College of Medicine : Complete secure experiment (animal experiment): The microorganism gene mutation analysis - is safe; The animal in vivo micronucleus analysis - is safe; In vitro chromosomic structure variation analysis - is safe.
  • The DMH carcinogen and the high fat feed induce the intestinal tumor prevention preparation experiment (animal experiment): May repair the spleen tissue and protect the kidney tissue.
  • The prevention tumor induced by the B 16F 10 cancer cell injection preparation experiment (animal experiment): Carries on.
  • Mechanism of analysis suppression tumor growth on Tumor Model Animals (animal experiment): Carries on.
  • Tumor medicine assistance experiment (animal experiment): Carries on.
  • China Medical University Hospital :Intestinal function improvement function appraisal (human body experiment): Is helpful to increases in the intestinal benefit bacteria.
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